하악골 골절에 대한 수술 시 예방적 항생제 사용과 술후 항생제 투여의 효율성

강상훈; 최영수; 변인영; 김문기

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하악골 골절에 대한 수술 시 예방적 항생제 사용과 술후 항생제 투여의 효율성
ANTIBIOTIC PROPHYLAXIS IN THE OPERATION OF THE CLOSED MANDIBULAR FRACTURES AND THE EFFICACY OF POSTOPERATIVE ANTIBIOTICS

대한구강악안면외과학회지 2009년 35권 1호 p.31 ~ 34

강상훈, 최영수, 변인영, 김문기,

소속 상세정보

강상훈 ( Kang Sang-Hoon ) - 국민건강보험공단 일산병원 구강악안면외과
최영수 ( Choi Young-Su ) - 국민건강보험공단 일산병원 구강악안면외과
변인영 ( Byun In-Young ) - 국민건강보험공단 일산병원 구강악안면외과
김문기 ( Kim Moon-Key ) - 국민건강보험공단 일산병원 구강악안면외과

KMID : 0355620090350010031

Abstract

Purpose: This study compared the frequency of postoperative infections in patients for a closed mandibular fracture with that without the postoperative antibiotic prophylaxis.
Patients and Methods: 48 patients without any specific medical history were divided into two groups depending on whether or not antibiotics had been applied after the surgery. The 24 patients in group 1 received only a second-generation cephalosporin (Cefotetan®) intravenously from admission to immediate after the surgery. Likewise, 24 patients in group 2 received 1.0g of Cefotetan® twice daily longer than the third day after surgery. The mean (SD) duration of antibiotics administration after surgery was 6.9 (±3.56). The patients were evaluated after surgery for any postoperative infections according to the criteria: purulent drainage from a wound, spontaneous wound dehiscence accompanied by swelling, pain, and fever around the wound.
Results: Postoperative infections were encountered in 2 out of 24 patients in group 1, who received antibiotic medication until shortly after surgery, and in 3 out of the 24 patients in group 2, in whom the medication was continued even after the surgery. There was no sig nificant difference in the incidence of postoperative infections between the two groups.
Conclusion: From this study, postoperative use of antibiotics seems to be unnecessary with view of the little significance of the factors that could affect the wound infection.